Here's my input on the wireframe: Currently you're using too many faces. I would recommend using less poly's, at least to begin with, to get the basis for your face.
Here is a great example image of what I mean. Start with something lower poly then build your details off of that. The main thing I currently notice about your model is that it's riddled with lots of imperfections. This comes from having too dense of a mesh, leaving you with much less control.
As for edge looping, you should try to get the loops coming from the chin to go either over the bridge of the nose or around the face (check out the image again for a color-coded reference on "key loops".) So I also recommend you get the loops around the eye to actually go fully around the eyes.
Don't take the amounts of criticism I have negatively. These are meant to help you, and I've done a good deal of studying up on face topology in particular. Good start, I hope to see improvements!
