It would be very neat to have a script for animated textures, like from a folder where you only specify the name (like frame) and the files (frame1, frame2 etc) would be loaded automatically loaded, with the option to loop or not (explosions, non looping, animated normalmap for water, looping)
or a packed square texture with all the frames in it should also be a possibility, that way animated materials with a animation tab in the material property window would be possible (the animation tab should have, framerate slider, and perhaps the ability to assign animated textures to effect slots like animated bump/transparancy/self illumination etc
would be neat